Enoxaparin binds to and potentiates antithrombin (a circulating anticoagulant) to form a complex that irreversibly inactivates clotting factor Xa. It has less activity against factor IIa (thrombin) compared to unfractionated heparin (UFH) due to its low molecular weight.
Side effects of enoxaparin include:
Postmarketing side effects of enoxaparin reported include:
Dosage of Enoxaparin:
Knee or hip replacement surgery
Medical patients with restricted mobility
If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.
Severe interactions of enoxaparin include:
Enoxaparin has serious interactions with at least 68 different drugs.
Enoxaparin has moderate interactions with at least 135 different drugs.
Mild interactions of enoxaparin include:
This medication contains enoxaparin. Do not take Lovenox if you are allergic to enoxaparin or any ingredients contained in this drug.
Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.
Epidural or spinal hematomas may occur in patient's anticoagulated with low-molecular-weight heparin (LMWH) or heparinoids who receive neuraxial (epidural/spinal) anesthesia or spinal puncture
These hematomas may result in long-term or permanent paralysis
Patients should be frequently monitored for signs and symptoms of neurologic impairment (tingling, numbness, muscular weakness)
If neurologic compromise is noted, urgent treatment is necessary
Physicians should consider the benefits versus risk before neuraxial intervention in patient's anticoagulated or to be anticoagulated for thromboprophylaxis
Factors increasing risk of epidural or spinal hematomas: