It is a form of penicillin which is a combination of benzylpenicillin and the local anaesthetic agent procaine. Following deep intramuscular injection, it is slowly absorbed into the circulation and hydrolysed to benzylpenicillin — thus it is used where prolonged low concentrations of benzylpenicillin are required.
Specific indications for procaine penicillin include:
At high doses procaine penicillin can cause seizures and CNS abnormalities due to procaine present in it.
Procaine penicillin must be injected slowly into a muscle of the buttock or upper thigh.
Do not inject the medication into a vein or life-threatening side effects could result.
Your procaine penicillin injections should be given at evenly spaced intervals.
Use this medication for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Procaine penicillin will not treat a viral infection such as the common cold or flu.
Call your doctor if your infection does not improve, or if it gets worse while using procaine penicillin.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
This medication can cause you to have unusual results with certain lab tests, including tests to check for glucose (sugar) in the urine. Tell any doctor who treats you that you are using procaine penicillin.
After you have finished your treatment with procaine penicillin, your doctor may want to do tests to make sure your infection has completely cleared up.
Store this medication in the refrigerator. Do not freeze. Do not use the mixed medication if it has changed colors or has any particles in it.
Seek emergency medical attention if you think you have used too much of this medicine. Overdose symptoms may include mood changes, agitation, confusion, and seizure (convulsions).
Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, stop using this medication and call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
Do not receive a "live" vaccine such as typhoid vaccine, cholera vaccine, or BCG (Bacillus Calmette and Guérin) vaccine.
Tell your doctor about all other medications you use, especially:
This list is not complete and there may be other drugs that
can interact with procaine penicillin. Tell your doctor about all the
prescription and over-the-counter medications you use. This includes vitamins,
minerals, herbal products, and drugs prescribed by other doctors. Do not start
using a new medication without telling your doctor.
Procaine penicillin is an antibiotic that fights bacteria in your body.
Procaine penicillin is used to treat many different types of infections caused by bacteria, including syphilis (a sexually transmitted disease).